CXCR1 Antibodies

AND CXCR1 ELISA kits, CXCR1 Proteins

Many biological assays use antibodies to detect CXCR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXCR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXCR1 antibodies...

We validate the specificity of these antibodies to CXCR1 by testing them on tissues known to express CXCR1 positively and negatively. Browse below to find the CXCR1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for CXCR1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CXCR1 Western Blot Guide

CXCR1 Infographic by Boster Bio

All CXCR1 Products

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Specificity

Applications

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Anti-CXCR1 Antibody Picoband®

1 Citations

Western blot analysis of CXCR1 using anti-CXCR1 antibody (PA2080)

Expressions of CXCL6, CXCR1, and CXCR2 in osteosarcoma (OS) cells

Human

Flow Cytometry, WB

$370
Cat # PA2080
100 μg/vial

CXCR1 (NM_000634) Human Over-expression Lysate

Human

$628
Cat # LS003577
20 µg, 100 µg

CXCR1 Overview

Facts about C-X-C chemokine receptor type 1.

CXCR1 3D structure. Source: alphafold

C-X-C chemokine receptor type 1 (CXCR1)

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils.

This response is mediated via a G-protein that trigger a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 using a high affinity and to MGSA (GRO) with a low affinity.

Gene Information

Human
Gene Name:	CXCR1
Uniprot:	P25024
Entrez:	3577

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CD128; CD181 antigen; CD181; CDw128aC-C; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; C-X-C chemokine receptor type 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 RA; IL-8 receptor type 1; IL-8R A; IL8R1; IL8RA; IL8RAC-C-CKR-1; IL8RBA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A

Molecular Weight

Mass (kDA):
39.791 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (218162841..218166962, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Inflammation
Neoplasms
Malignant Neoplasms
Tumor Angiogenesis
Tissue Adhesions
Neoplasm Metastasis
Cholangiocarcinoma
Infective Disorder
Lung Diseases
Pathologic Neovascularization
Inflammatory Response
Malignant Paraganglionic Neoplasm

Melanoma
Chronic Obstructive Airway Disease
Arthritis
Lung Diseases, Obstructive
Carcinoma
Asthma
Rheumatoid Arthritis

Pathways

Chemotaxis
Pathogenesis
Angiogenesis
Secretion
Cell Migration
Inflammatory Response
Neutrophil Chemotaxis
Cell Proliferation
Immune Response
Neutrophil Activation
Receptor Internalization
Leukocyte Migration
Wound Healing

Phagocytosis
Chemokine Production
Localization
Cell Growth
Exocytosis
Cell Activation
Cell Chemotaxis

PTMs

Phosphorylation
Cleavage
Formylation

Glycosylation
Methylation
Amidation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXCR1

References

PMID: 1840701 by Holmes W.E., et al. Structure and functional expression of a human interleukin-8 receptor.

PMID: 8384312 by Cerretti D.P., et al. Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2.

2 Publications of Boster CXCR1 Antibodies & ELISA Kits

PubMed ID: 28610419, Gene Expression Profiling of Chemokines and Their Receptors in Low and High Grad...
PubMed ID: 30086759, IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular...

*More publications can be found for each product on its corresponding product page