CXCR6 Antibodies

AND CXCR6 ELISA kits, CXCR6 Proteins

Many biological assays use antibodies to detect CXCR6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXCR6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXCR6 antibodies...

We validate the specificity of these antibodies to CXCR6 by testing them on tissues known to express CXCR6 positively and negatively. Browse below to find the CXCR6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CXCR6 Infographic by Boster Bio

All CXCR6 Products

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Product

Figures

Specificity

Applications

Price

Anti-Bonzo/CXCR6 Antibody Picoband®

Human

IHC, WB

$370
Cat # PA2082
100 μg/vial

Anti-CXCR6 / CD186 Rabbit Monoclonal Antibody

Human

$370
Cat # M02517
100 µl/vial

CXCR6 Overview

Facts about C-X-C chemokine receptor type 6.

CXCR6 3D structure. Source: alphafold

C-X-C chemokine receptor type 6 (CXCR6)

Receptor for the C-X-C chemokine CXCL16.
Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.

Gene Information

Human
Gene Name:	CXCR6
Uniprot:	O00574
Entrez:	10663

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Bonzo; BONZOG-protein coupled receptor bonzo; CD186 antigen; CD186; CDw186; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXCR6; CXC-R6; CXCR-6; G protein-coupled receptor; STRL33; STRL33G-protein coupled receptor STRL33; TYMSTRCD186

Molecular Weight

Mass (kDA):
39.28 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (45940688..45948354)

Tissue Specificity

Expressed in lymphoid tissues and activated T cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hiv Infections
Inflammation
Neoplasms
Immunologic Deficiency Syndromes
Tissue Adhesions
Malignant Neoplasms
Neoplasm Metastasis
Acquired Immunodeficiency Syndrome
Carcinoma
Atherosclerosis
Cell Invasion
Hepatitis

Arthritis
Autoimmune Reaction
Cholangiocarcinoma
Simian Acquired Immunodeficiency Syndrome
Melanoma
Prostatic Neoplasms

Pathways

Pathogenesis
Chemotaxis
Secretion
Cell Migration
Cell Adhesion
Tropism
Localization
Cell Activation
Cell Proliferation
Immune Response
T Cell Migration
Cytokine Production
Angiogenesis

T Cell Activation
Cell Differentiation
T Cell Differentiation
Inflammatory Response
Cell Growth
Cell-cell Adhesion
Regeneration

PTMs

Phosphorylation

Cleavage

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXCR6

References

PMID: 9230441 by Deng H.K., et al. Expression cloning of new receptors used by simian and human immunodeficiency viruses.

PMID: 9166430 by Liao F., et al. STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV- 1.