CXXC5 Antibodies

AND CXXC5 ELISA kits, CXXC5 Proteins

Many biological assays use antibodies to detect CXXC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXXC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXXC5 antibodies...

We validate the specificity of these antibodies to CXXC5 by testing them on tissues known to express CXXC5 positively and negatively. Browse below to find the CXXC5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for CXXC5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CXXC5 IHC Guide

CXXC5 Infographic by Boster Bio

All CXXC5 Products

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Specificity

Applications

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Anti-CXXC5 Antibody Picoband®

Western blot analysis of CXXC5 using anti-CXXC5 antibody (A06865-1)

IHC analysis of CXXC5 using anti-CXXC5 antibody (A06865-1)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A06865-1
100 μg/vial

Anti-CXXC5 Antibody

Western blot analysis of CXXC5 in human brain tissue lysate with CXXC5 antibody at 1 μg/mL

Immunohistochemistry of CXXC5 in human brain tissue with CXXC5 antibody at 2

Immunofluorescence of CXXC5 in Human Brain tissue with CXXC5 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A06865
0.1 mg

CXXC5 (NM_016463) Human Over-expression Lysate

Human

$628
Cat # LS051523
20 µg, 100 µg

CXXC5 Overview

Facts about CXXC-type zinc finger protein 5.

CXXC5 3D structure. Source: alphafold

CXXC-type zinc finger protein 5 (CXXC5)

May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity).

Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.

Gene Information

Human
Gene Name:	CXXC5
Uniprot:	Q7LFL8
Entrez:	51523

Family

Belongs to:

No superfamily

Alternative Names

CF5; CXXC finger 5 protein; CXXC finger 5; CXXC finger protein 5; CXXC-type zinc finger protein 5; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor; RINF; WID; WT1-induced Inhibitor of Dishevelled

Molecular Weight

Mass (kDA):
32.977 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (139647299..139683885)

Subcellular Localizations

Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.

Diseases

Neoplasms
Malignant Neoplasms
Myeloid Leukemia
Leukemia
Infertility
Leukemia, Myelocytic, Acute
Dysmyelopoietic Syndromes
Premature Menopause
Myelomonocytic Leukemia
Melanoma
Malignant Neoplasm Of Breast
Ataxia
Colonic Neoplasms

Malignant Tumor Of Colon
Carcinoma
Cardiovascular Diseases
Blepharoptosis
Acute Promyelocytic Leukemia
Blepharophimosis
Mammary Neoplasms

Pathways

Pathogenesis
Senescence
Egg Activation
Cell Cycle
Cell Death
Dna Repair
Ovulation
Rna Interference

Localization
Cell Cycle Arrest
Kidney Development

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXXC5

References

PMID: 19557330 by Zhang M., et al. The CXXC finger 5 protein is required for DNA damage-induced p53 activation.

PMID: 12761501 by Matsuda A., et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.