Cytochrome P450 4A22 Antibodies

AND CYP4A22 ELISA kits, Cytochrome P450 4A22 Proteins

Many biological assays use antibodies to detect Cytochrome P450 4A22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 4A22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 4A22 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 4A22 by testing them on tissues known to express CYP4A22 positively and negatively. Browse below to find the CYP4A22 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP4A22 Infographic by Boster Bio

All CYP4A22 Products

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Product

Figures

Specificity

Applications

Price

Anti-CP4AM CYP4A22 Antibody

Human

ELISA, WB

$380
Cat # A08701
100ul

CYP4A22 (NM_001010969) Human Over-expression Lysate

Human

$960
Cat # LS284541
20 µg, 100 µg

CYP4A22 Overview

Facts about Cytochrome P450 4A22.

CYP4A22 3D structure. Source: alphafold

Cytochrome P450 4A22 (CYP4A22)

Catalyzes the omega- and (omega-1)-hydroxylation of different fatty acids like laurate and palmitate. Shows no action involving arachidonic acid and prostaglandin A1.

Lacks functional activity in the kidney and doesn't contribute to renal 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis. .

Gene Information

Human
Gene Name:	CYP4A22
Uniprot:	Q5TCH4
Entrez:	284541

Family

Belongs to:

cytochrome P450 family

Alternative Names

CYPIVA22; cytochrome P450 4A22K; cytochrome P450, family 4, subfamily A, polypeptide 22

Molecular Weight

Mass (kDA):
59.246 kDA

Genomic Context


Human

Location:	1p33
Sequence:	1; NC_000001.11 (47137425..47149738)

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Diseases

Hypertensive Disease
Pathologic Vasoconstriction
Renal Vascular Disorder
Fatty Liver
Atrophy Of Testis
Liver Carcinoma
Atrophy
Steatosis
Inflammation
Hypotension Adverse Event
Reperfusion Injury
Essential Hypertension

Neoplasm Metastasis
Stenosis
Non-neoplastic Disorder
Melanoma
Malignant Neoplasm Of Breast
Swine Diseases
Carotid Artery Injuries

Pathways

Vasoconstriction
Regulation Of Blood Pressure
Translation
Excretion
Transport
Induction Of Apoptosis
Tube Formation
Conjugation
Spermatogenesis
Glomerular Filtration
Fatty Acid Homeostasis

Reverse Transcription
Sensitization
Angiogenesis
Mrna Polyadenylation
Pathogenesis

PTMs

Oxidation

Hydroxylation

Nitration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP4A22

References

PMID: 10860550 by Kawashima H., et al. Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.

PMID: 15611369 by Gainer J.V., et al. Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.