Cytochrome P450 4F11 Antibodies

AND CYP4F11 ELISA kits, Cytochrome P450 4F11 Proteins

Many biological assays use antibodies to detect Cytochrome P450 4F11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 4F11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 4F11 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 4F11 by testing them on tissues known to express CYP4F11 positively and negatively. Browse below to find the CYP4F11 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP4F11 Infographic by Boster Bio

All CYP4F11 Products

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CYPIVF11 (CYP4F11) (NM_021187) Human Recombinant Protein

Coomassie blue staining of purified CYP4F11 protein

$1249
Cat # PROTQ9HBI6
20 µg

CYPIVF11 (CYP4F11) (NM_021187) Human Over-expression Lysate

CYPIVF11 (CYP4F11) Human Over-expression Lysates NM_001128932

Human

$628
Cat # LS057834
20 µg, 100 µg

Anti-CYP4F11 Antibody

Human

ELISA, IF, IHC, ICC, WB

$370
Cat # A09078-2
100 μl/vial

CYP4F11 Overview

Facts about Cytochrome P450 4F11.

CYP4F11 3D structure. Source: alphafold

Cytochrome P450 4F11 (CYP4F11)

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a crucial role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2.

Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081).

Gene Information

Human
Gene Name:	CYP4F11
Uniprot:	Q9HBI6
Entrez:	57834

Family

Belongs to:

cytochrome P450 family

Alternative Names

CYPIVF11; cytochrome P450 4F11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; EC 1.14.14.1

Molecular Weight

Mass (kDA):
60.146 kDA

Genomic Context


Human

Location:	19p13.12
Sequence:	19; NC_000019.10 (15912370..15934866, complement)

Tissue Specificity

Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.

Diseases

Liver Carcinoma
Malignant Neoplasm Of Breast
Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Cholangiocarcinoma
Cell Transformation, Neoplastic
Carcinoma

Obesity
Hyperglycemia
Refractory Anemia With Ringed Sideroblasts

Pathways

Protein Phosphorylation
Translation
Fatty Acid Beta-oxidation

PTMs

Phosphorylation

Hydroxylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP4F11

References

PMID: 10964514 by Cui X., et al. A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization.

PMID: 15364545 by Kalsotra A., et al. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.