Cbx8 Antibodies

AND Cbx8 ELISA kits, Cbx8 Proteins

Many biological assays use antibodies to detect Cbx8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cbx8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cbx8 antibodies...

We validate the specificity of these antibodies to Cbx8 by testing them on tissues known to express Cbx8 positively and negatively. Browse below to find the Cbx8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Cbx8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CBX8 Western Blot Guide

Cbx8 Infographic by Boster Bio

All Cbx8 Products

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Applications

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Anti-Cbx8 Antibody Picoband®

Western blot analysis of Cbx8 using anti-Cbx8 antibody (A05234-2)

IHC analysis of Cbx8 using anti-Cbx8 antibody (A05234-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05234-2
100 μg/vial

Anti-Cbx8 Antibody Picoband® (monoclonal, 8G7)

Western blot analysis of Cbx8 using anti-Cbx8 antibody (M05234)

IHC analysis of Cbx8 using anti-Cbx8 antibody (M05234)

Flow Cytometry analysis of HL-60 cells using anti-Cbx8 antibody (M05234)

Human

Flow Cytometry, IHC, WB

$370
Cat # M05234
100 μg/vial

CBX8 (NM_020649) Human Over-expression Lysate

Human

$628
Cat # LS057332
20 µg, 100 µg

Cbx8 Overview

Facts about Chromobox protein homolog 8.

Chromobox protein homolog 8 (Cbx8)

Part of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class necessary to keep the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts through chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

Gene Information

Mouse
Gene Name:	Cbx8
Uniprot:	Q9QXV1
Entrez:	30951

Family

Belongs to:

No superfamily

Alternative Names

chromobox homolog 8 (Drosophila Pc class); chromobox homolog 8 (Pc class homolog, Drosophila); chromobox homolog 8; HPC3; Pc3; PC3chromobox protein homolog 8; Polycomb 3 homolog; polycomb 3; RC1Pc class 3 homolog; Rectachrome 1

Molecular Weight

Mass (kDA):
39.86 kDA

Genomic Context


Mouse

Location:	11\|11 E2
Sequence:	11;

Diseases

Malignant Neoplasms
Leukemia
Cell Transformation, Neoplastic
Leukemogenesis
Chromosomal Translocation
Malignant Neoplasm Of Prostate
Malignant Paraganglionic Neoplasm
Virus Diseases
Acute Biphenotypic Leukemia

Prostatic Neoplasms
Neoplasms
Myeloid Leukemia

Pathways

Methylation
Senescence
Gene Silencing
Chromatin Modification
Localization
Dna Hypermethylation
Cellular Senescence
Dna Methylation

Cell Growth
Histone Modification
Oncogenesis

PTMs

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cbx8

References

PMID: 10721694 by Hemenway C.S., et al. Identification and analysis of a third mouse Polycomb gene, MPc3.

PMID: 16359901 by Cao R., et al. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.