Clybl Antibodies

AND Clybl ELISA kits, Clybl Proteins

Many biological assays use antibodies to detect Clybl, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clybl in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clybl antibodies...

We validate the specificity of these antibodies to Clybl by testing them on tissues known to express Clybl positively and negatively. Browse below to find the Clybl antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Clybl Infographic by Boster Bio

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CLYBL (NM_206808) Human Over-expression Lysate

Human

$628
Cat # LS171425
20 µg, 100 µg

Clybl Overview

Facts about Citramalyl-CoA lyase, mitochondrial.

Citramalyl-CoA lyase, mitochondrial (Clybl)

Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism (PubMed:29056341). Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5- dicarboxylate catabolism pathway (By similarity).

The C5- dicarboxylate catabolism pathway is needed to detoxify itaconate, a vitamin B12-poisoning metabolite (PubMed:29056341). Also functions as a malate synthase in vitro, converting glyoxylate and acetyl-CoA into malate (By similarity).

Gene Information

Mouse
Gene Name:	Clybl
Uniprot:	Q8R4N0
Entrez:	69634

Family

Belongs to:

HpcH/HpaI aldolase family

Alternative Names

citrate lyase beta like; EC 4.1; mitochondrial

Molecular Weight

Mass (kDA):
37.549 kDA

Genomic Context


Mouse

Location:	14\|14 E5
Sequence:	14;

Tissue Specificity

Detected in brown fat, brain, liver, kidney, heart, skeletal muscle and ovary (at protein level).

Diseases

Gastrointestinal Diseases
Cardiovascular Diseases
Anemia
Neurodegenerative Disorders
Anemia, Pernicious

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Clybl

References

PMID: 11741334 by Morikawa J., et al. Molecular cloning of novel mouse and human putative citrate lyase beta-subunit.

PMID: 18614015 by Pagliarini D.J., et al. A mitochondrial protein compendium elucidates complex I disease biology.