COMMD4 Antibodies

AND COMMD4 ELISA kits, COMMD4 Proteins

Many biological assays use antibodies to detect COMMD4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COMMD4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COMMD4 antibodies...

We validate the specificity of these antibodies to COMMD4 by testing them on tissues known to express COMMD4 positively and negatively. Browse below to find the COMMD4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COMMD4 Infographic by Boster Bio

All COMMD4 Products

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Specificity

Applications

Price

COMMD4 (NM_017828) Human Recombinant Protein

Coomassie blue staining of purified COMMD4 protein

$1062
Cat # PROTQ9H0A8
20 µg

COMMD4 (NM_017828) Human Over-expression Lysate

Human

$628
Cat # LS054939
20 µg, 100 µg

COMMD4 Overview

Facts about COMM domain-containing protein 4.

COMMD4 3D structure. Source: alphafold

COMM domain-containing protein 4 (COMMD4)

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B.

Gene Information

Human
Gene Name:	COMMD4
Uniprot:	Q9H0A8
Entrez:	54939

Family

Belongs to:

No superfamily

Alternative Names

COMM domain containing 4; COMM domain-containing protein 4; FLJ20452

Molecular Weight

Mass (kDA):
21.764 kDA

Genomic Context


Human

Location:	15q24.2
Sequence:	15; NC_000015.10 (75336035..75343227)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Hypertrophic Cardiomyopathy
Cardiomyopathies
Hypertrophy

Interacting Proteins

CCDC22
COMMD1
COMMD8

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COMMD4

References

PMID: 15799966 by Burstein E., et al. COMMD proteins, a novel family of structural and functional homologs of MURR1.

PMID: 21778237 by Mao X., et al. COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.