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- Table of Contents
Facts about CST complex subunit CTC1.
Initially the CST complex was proposed to protect telomeres from DNA degradation (PubMed:19854130). However, the CST complex was demonstrated to be involved in several facets of telomere replication.
| Mouse | |
|---|---|
| Gene Name: | Ctc1 |
| Uniprot: | Q5SUQ9 |
| Entrez: | 68964 |

| Belongs to: |
|---|
| CTC1 family |

CST complex subunit CTC1
Mass (kDA):
134.028 kDA

| Mouse | |
|---|---|
| Location: | 11|11 B3 |
| Sequence: | 11; |

PMID: 19119139 by Casteel D.E., et al. A DNA polymerase-{alpha}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells.
PMID: 19854130 by Miyake Y., et al. RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.