Cathepsin 8 Antibodies

AND Cts8 ELISA kits, Cathepsin 8 Proteins

Many biological assays use antibodies to detect Cathepsin 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cathepsin 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cathepsin 8 antibodies...

We validate the specificity of these antibodies to Cathepsin 8 by testing them on tissues known to express Cts8 positively and negatively. Browse below to find the Cts8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cts8 Infographic by Boster Bio

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Cts8 Overview

Facts about Cathepsin 8.

Cts8 3D structure. Source: alphafold

Cathepsin 8 (Cts8)

Probable protease (By similarity). In placenta, plays a role in boosting giant cell differentiation (PubMed:18776147).

Also plays a role in placental spiral artery remodeling by direct degradation of smooth muscle alpha-actin (PubMed:18776147). .

Gene Information

Mouse
Gene Name:	Cts8
Uniprot:	Q9JI81
Entrez:	56094

Family

Belongs to:

peptidase C1 family

Alternative Names

Cathepsin 8

Molecular Weight

Mass (kDA):
37.803 kDA

Genomic Context


Mouse

Location:	13\|13 B2
Sequence:	13;

Tissue Specificity

Expressed in placenta (PubMed:11829493, PubMed:10885754, PubMed:18776147). Highly expressed in a subset of trophoblast giant cells in the parietal yolk sac and at the outside of the ectoplacental cone (PubMed:10885754). Expressed at highest level in liver with lesser amounts in testis, kidney, heart, lung and brain (PubMed:10885754). Not detected in spleen and skeletal muscle (PubMed:10885754, PubMed:11829493). Not detected in blood, heart, brain, testis, liver, lung, kidney, thymus or uterus (PubMed:11829493).

PTMs

Disulfide bond

Glycoprotein

Zymogen

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cts8

References

PMID: 10885754 by Hemberger M., et al. cDNA subtraction cloning reveals novel genes whose temporal and spatial expression indicates association with trophoblast invasion.

PMID: 11829493 by Deussing J., et al. Identification and characterization of a dense cluster of placenta- specific cysteine peptidase genes and related genes on mouse chromosome 13.