- Table of Content
|DNA repair metallo-beta-lactamase (DRMBL) family|
|Sequence:||10; NC_000010.11 (113834725..113854394, complement)|
Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle.
Nucleus. In some cells it may be found in typically 1 or 2 discrete nuclear aggregates of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in number following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with those formed by the MRN complex (composed of MRE11, RAD50 and NBN) and BRCA1.