DDRGK1 Antibodies

AND DDRGK1 ELISA kits, DDRGK1 Proteins

Many biological assays use antibodies to detect DDRGK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDRGK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDRGK1 antibodies...

We validate the specificity of these antibodies to DDRGK1 by testing them on tissues known to express DDRGK1 positively and negatively. Browse below to find the DDRGK1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: MRPS34

DDRGK1 Infographic by Boster Bio

All DDRGK1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DDRGK1 Antibody

Human, Mouse

ELISA, IF, IHC, ICC, WB

$370
Cat # A09155-2
100 μl/vial

DDRGK1 Overview

Facts about DDRGK domain-containing protein 1.

DDRGK1 3D structure. Source: alphafold

DDRGK domain-containing protein 1 (DDRGK1)

Protein that interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. During TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498).

May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:23675531). May also play a role in the cellular response to endoplasmic reticulum stress (By similarity).

Gene Information

Human
Gene Name:	DDRGK1
Uniprot:	Q96HY6
Entrez:	65992

Family

Belongs to:

DDRGK1 family

Alternative Names

C20orf116; chromosome 20 open reading frame 116; DDRGK domain containing 1; DDRGK domain-containing protein 1; dJ1187M17.3; MGC2592

Molecular Weight

Mass (kDA):
35.611 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (3190350..3204682, complement)

Tissue Specificity

Widely expressed (at protein level). In the brain, highest levels in medulla oblongata, followed by cerebral cortex, cerebellum and frontal lobe.

Subcellular Localizations

Endoplasmic reticulum.

Diseases

Cholangiocarcinoma
Cell Invasion
Hepatitis, Chronic
Neoplasms
Hepatitis
Hepatitis C, Chronic
Hepatitis C

Dysequilibrium Syndrome

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDRGK1

References

PMID: 20036718 by Neziri D., et al. Cloning and molecular characterization of Dashurin encoded by C20orf116, a PCI-domain containing protein.

PMID: 20018847 by Tatsumi K., et al. A novel type of E3 ligase for the Ufm1 conjugation system.