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DDX3Y Antibodies
AND DDX3Y ELISA kits, DDX3Y Proteins
Many biological assays use antibodies to detect DDX3Y, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDX3Y in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDX3Y antibodies...
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DDX3Y Infographic by Boster Bio
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DDX3Y Overview
Facts about ATP-dependent RNA helicase DDX3Y.
ATP-dependent RNA helicase DDX3Y (DDX3Y)
Probable ATP-dependent RNA helicase.
May play a role in spermatogenesis..
Gene Information
| Human | |
|---|---|
| Gene Name: | DDX3Y |
| Uniprot: | O15523 |
| Entrez: | 8653 |
Family
| Belongs to: |
|---|
| DEAD box helicase family |
Alternative Names
ATP-dependent RNA helicase DDX3Y; DBYEC 3.6.4.13; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DEAD box protein 3, Y-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; EC 3.6.1
Molecular Weight
Mass (kDA):
73.154 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Yq11.221 |
| Sequence: | Y; NC_000024.10 (12903999..12920478) |
Tissue Specificity
Testis-specific. Expressed predominantly in spermatogonia.
Subcellular Localizations
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.
Diseases
- Azoospermia
- Congenital Absence Of Germinal Epithelium Of Testes
- Graft-vs-host Disease
- Infertility
- Oligospermia
- Male Infertility
- Leukemia
- Neoplasms
- Steroid Sulfatase Deficiency Disease
- Carcinoma
- Malignant Neoplasms
- Chromosome Breakage
Pathways
- Spermatogenesis
- Translation
- Localization
- Immune Response
- Cell Cycle
- Transport
- Transposition
- Fertilization
- Brain Development
- Sex Determination
- Reverse Transcription
- System Development
- Cell Differentiation
PTMs
- Acetylation
- Isopeptide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDX3Y
bosterbio.com/bosterbio-gene-info-cards/DDX3Y
References
PMID: 9381176 by Lahn B.T., et al. Functional coherence of the human Y chromosome.
PMID: 15383328 by Sekiguchi T., et al. Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation.