Deformed epidermal autoregulatory factor 1 homolog (DEAF1)

Transcription factor that binds to sequence with many copies of 5'-TTC[CG]G-3' present in its promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes.

Binds to the retinoic acid response element (RARE) 5'- AGGGTTCACCGAAAGTTCA-3'. When secreted, acts as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.