Dedd2 Antibodies

AND Dedd2 ELISA kits, Dedd2 Proteins

Many biological assays use antibodies to detect Dedd2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dedd2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dedd2 antibodies...

We validate the specificity of these antibodies to Dedd2 by testing them on tissues known to express Dedd2 positively and negatively. Browse below to find the Dedd2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dedd2 Infographic by Boster Bio

All Dedd2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DEDD2 (DED4) Antibody

1 Q&As

Canine, Human, Mouse, Rat

$387
Cat # A11263
50 µl

DEDD2 (NM_133328) Human Over-expression Lysate

Human

$628
Cat # LS162989
20 µg, 100 µg

Dedd2 Overview

Facts about DNA-binding death effector domain-containing protein 2.

DNA-binding death effector domain-containing protein 2 (Dedd2)

May play a critical role in passing receptor-induced apoptosis and may target CASP8 and CASP10 into the nucleus. May regulate degradation of intermediate filaments during apoptosis.

May play a part in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. .

Gene Information

Mouse
Gene Name:	Dedd2
Uniprot:	Q8QZV0
Entrez:	67379

Family

Belongs to:

No superfamily

Alternative Names

death effector domain containing 2; death effector domain-containing DNA binding protein 2; DED-containing protein FLAME-3; DNA-binding death effector domain-containing protein 2; FADD-like apoptotic molecule 3; FLAME3; FLAME-3

Molecular Weight

Mass (kDA):
36.786 kDA

Genomic Context


Mouse

Location:	7\|7 A3
Sequence:	7;

Tissue Specificity

Expression is high in liver, heart, kidney, and testis but low in brain, spleen, lung, and skeleton muscle.

Diseases

Malignant Neoplasms
Neoplasms
Bulla

Pathways

Cell Death
Localization
Sensitization
Cell Proliferation
Programmed Cell Death
Cell Cycle

PTMs

Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dedd2

References

PMID: 11965497 by Zhan Y., et al. Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC.

PMID: 12527898 by Alcivar A., et al. DEDD and DEDD2 associate with caspase-8/10 and signal cell death.