Defensin-5 Antibodies

AND DEFA5 ELISA kits, Defensin-5 Proteins

Many biological assays use antibodies to detect Defensin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Defensin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Defensin-5 antibodies...

We validate the specificity of these antibodies to Defensin-5 by testing them on tissues known to express DEFA5 positively and negatively. Browse below to find the DEFA5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEFA5 Infographic by Boster Bio

All DEFA5 Products

Product

Figures

Specificity

Applications

Price

alpha 5 Defensin (DEFA5) (NM_021010) Human Over-expression Lysate

Human

$628
Cat # LS001670
100 µg

DEFA5 Overview

Facts about Defensin-5.

DEFA5 3D structure. Source: alphafold

Defensin-5 (DEFA5)

Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. .

Gene Information

Human
Gene Name:	DEFA5
Uniprot:	Q01523
Entrez:	1670

Family

Belongs to:

alpha-defensin family

Alternative Names

alpha-Defensin 5; DEF5; DEF5defensin, alpha 5, preproprotein; DEFA5; defensin 5; Defensin alpha 5; Defensin, alpha 5; defensin, alpha 5, Paneth cell-specific; defensin-5; HD-5; MGC129728

Molecular Weight

Mass (kDA):
10.071 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (7055304..7056739, complement)

Tissue Specificity

Paneth cells of the small intestine (at protein level).

Subcellular Localizations

Secreted. Cytoplasmic vesicle, secretory vesicle. Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.