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- Table of Contents
DGAT1 Antibodies
AND DGAT1 ELISA kits, DGAT1 Proteins
Many biological assays use antibodies to detect DGAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DGAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DGAT1 antibodies...
Designing a Western blot for DGAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DGAT1 Western Blot GuideDesigning an IHC experiment for DGAT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the DGAT1 IHC GuideDGAT1 Infographic by Boster Bio
All DGAT1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02522
100 μl/vial
Cat # M02522
100 μl/vial
DGAT1 Overview
Facts about Diacylglycerol O-acyltransferase 1.
Diacylglycerol O-acyltransferase 1 (DGAT1)
Catalyzes the terminal and just dedicated step in triacylglycerol synthesis with diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival.
May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol.
Gene Information
| Human | |
|---|---|
| Gene Name: | DGAT1 |
| Uniprot: | O75907 |
| Entrez: | 8694 |
Family
| Belongs to: |
|---|
| membrane-bound acyltransferase family |
Alternative Names
ACAT-related gene product 1; AGRP1; ARAT; ARGP1; ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1; DGAT; DGAT1; DGATACAT related gene product 1; diacylglycerol O-acyltransferase 1; diacylglycerol O-acyltransferase homolog 1 (mouse); diacylglycerol O-acyltransferase homolog 1; DIAR7; Diglyceride acyltransferase; EC 2.3.1; EC 2.3.1.20
Molecular Weight
Mass (kDA):
55.278 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q24.3 |
| Sequence: | 8; NC_000008.11 (144314584..144326852, complement) |
Subcellular Localizations
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Diseases
- Obesity
- Insulin Resistance
- Steatosis
- Diabetes Mellitus
- Insulin Sensitivity
- Fatty Liver
- Steatohepatitis
- Diabetes Mellitus, Non-insulin-dependent
- Dysequilibrium Syndrome
- Impaired Glucose Tolerance
- Metabolic Diseases
- Liver Carcinoma
- Liver Diseases
Pathways
- Secretion
- Fatty Acid Oxidation
- Lactation
- Transport
- Seed Development
- Localization
- Energy Homeostasis
- Fatty Acid Transport
- Lipid Storage
- Insemination
- Germination
- Pathogenesis
- Insulin Secretion
PTMs
- Oxidation
- Acylation
- Phosphorylation
Research Areas
- Cancer
- Diabetes Research
- Lipid and Metabolism
- Lipid Droplets
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGAT1
bosterbio.com/bosterbio-gene-info-cards/DGAT1
References
PMID: 9756920 by Oelkers P., et al. Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.
PMID: 16214399 by Orland M.D., et al. Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.