Diacylglycerol O-acyltransferase 1 (DGAT1)

Catalyzes the terminal and just dedicated step in triacylglycerol synthesis with diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival.

May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol.