DHX33 Antibodies

AND DHX33 ELISA kits, DHX33 Proteins

Many biological assays use antibodies to detect DHX33, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DHX33 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DHX33 antibodies...

We validate the specificity of these antibodies to DHX33 by testing them on tissues known to express DHX33 positively and negatively. Browse below to find the DHX33 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DHX33 Infographic by Boster Bio

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DHX33 (NM_020162) Human Over-expression Lysate

Human

$960
Cat # LS056919
20 µg, 100 µg

DHX33 Overview

Facts about ATP-dependent RNA helicase DHX33.

DHX33 3D structure. Source: alphafold

ATP-dependent RNA helicase DHX33 (DHX33)

Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruiting (PubMed:21930779).

In the cytoplasm, promotes elongation-competent 80S ribosome assembly in the late phase of mRNA translation initiation (PubMed:26100019). Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells (PubMed:23871209).

Gene Information

Human
Gene Name:	DHX33
Uniprot:	Q9H6R0
Entrez:	56919

Family

Belongs to:

DEAD box helicase family

Alternative Names

DDX33; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 33; DEAH (Asp-Glu-Ala-His) box polypeptide 33; DEAH box protein 33; DKFZp762F2011; EC 3.6.1; EC 3.6.4.13; FLJ21972; putative ATP-dependent RNA helicase DHX33

Molecular Weight

Mass (kDA):
78.874 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (5440917..5469055, complement)

Subcellular Localizations

Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Nucleus. Inflammasome. Predominantly in the nucleolus. During mitosis, localizes with the nucleolar organizing regions (PubMed:21930779). Upon dsRNA-binding, localizes in the inflammasome (PubMed:23871209).

Pathways

Cell Growth
Rna Interference
Rrna Transcription

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DHX33

References

PMID: 21930779 by Zhang Y., et al. Identification of DHX33 as a mediator of rRNA synthesis and cell growth.

PMID: 23871209 by Mitoma H., et al. The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome.