- Table of Content
Implicated in a novel signal transduction pathway, where isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. .
|formin homology family|
|Sequence:||X; NC_000023.11 (96684663..97604997)|
Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
[Isoform 3]: Cytoplasm, cytosol. Early endosome. Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.