DIDO1 Antibodies

AND DIDO1 ELISA kits, DIDO1 Proteins

Many biological assays use antibodies to detect DIDO1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DIDO1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DIDO1 antibodies...

We validate the specificity of these antibodies to DIDO1 by testing them on tissues known to express DIDO1 positively and negatively. Browse below to find the DIDO1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for DIDO1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the DIDO1 IHC Guide

DIDO1 Infographic by Boster Bio

All DIDO1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Dio-1 (S186) DIDO1 Antibody

Western blot (WB) analysis of Dio-1 (S186) pAb at 1:500 dilution
Lane1:PC3 whole cell lysate(20ug)
Lane2:HEK293T whole cell lysate(20ug)
Lane3:C6 whole cell lysate(40ug)
Lane4:CT26 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Dio-1 (S186) pAb in paraffin-embedded human breast carcinoma tissue at 1:50

Human, Mouse, Rat

IHC, WB

$405
Cat # A06019S186
100ul

Anti-Dio-1 DIDO1 Antibody

Western Blot analysis of various cells using Dio-1 Polyclonal Antibody diluted at 1:2000

Western blot analysis of lysates from 293 cells, using DIDO1 Antibody

Western blot analysis of the lysates from HepG2 cells using DNL1 antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A06019
100ul

Anti-DIDO1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # A06019-1
100 μl/vial

DIDO1 Overview

Facts about Death-inducer obliterator 1.

DIDO1 3D structure. Source: alphafold

Death-inducer obliterator 1 (DIDO1)

Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor.

Required for early embryonic stem cell development. .

Gene Information

Human
Gene Name:	DIDO1
Uniprot:	Q9BTC0
Entrez:	11083

Family

Belongs to:

No superfamily

Alternative Names

BYE1; C20orf158; DATF1; DATF-1; DATF1DIDO3; death associated transcription factor 1; death inducer-obliterator 1; Death-associated transcription factor 1; death-inducer obliterator 1; DIDO1; DIO1; DIO1DIDO2; DIO-1hDido1; dJ885L7.8; DKFZp434P1115; FLJ11265; KIAA0333chromosome 20 open reading frame 158; MGC16140

Molecular Weight

Mass (kDA):
243.873 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (62877738..62937952, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis.

Diseases

Malignant Neoplasms
Neoplasms
Carcinogenesis
Adenoma
Tumor Progression
Carcinoma
Colorectal Cancer
Myelodysplastic-myeloproliferative Diseases
Colorectal Adenoma
Dysmyelopoietic Syndromes
Hematologic Neoplasms
Cell Transformation, Neoplastic

Colorectal Neoplasms
Instabilities, Chromosomal
Mood Disorders
Malignant Neoplasm Of Breast
Aneuploidy
Single Gene Defect
Chromosome Breakage

Pathways

Localization
Cell Death
Response To Stress
Cell Proliferation
Induction Of Apoptosis
Mitosis
Neurogenesis
Synaptic Transmission
Limb Development
Protein Metabolic Process
Cell Division
Metabolic Process

Cell Growth
Spindle Assembly Checkpoint
Rna Processing
Pathogenesis
Chromatin Remodeling
Spindle Assembly

PTMs

Cleavage

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DIDO1

References

PMID: 16127461 by Futterer A., et al. Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms.

PMID: 23831028 by Gatchalian J., et al. Dido3 PHD modulates cell differentiation and division.