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Dynein has ATPase activity; the force-producing power stroke is supposed to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (PubMed:24360805).
|dynein heavy chain family|
|Sequence:||3; NC_000003.12 (52313010..52400497)|
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain (PubMed:11175280).
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.