DNAH7 Antibodies

AND DNAH7 ELISA kits, DNAH7 Proteins

Many biological assays use antibodies to detect DNAH7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNAH7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNAH7 antibodies...

We validate the specificity of these antibodies to DNAH7 by testing them on tissues known to express DNAH7 positively and negatively. Browse below to find the DNAH7 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DNAH7 Overview

Facts about Dynein heavy chain 7, axonemal.

Dynein heavy chain 7, axonemal (DNAH7)

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.

Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). .

Gene Information

Human
Gene Name:	DNAH7
Uniprot:	Q8WXX0
Entrez:	56171

Family

Belongs to:

dynein heavy chain family

Alternative Names

axonemal dynein heavy chain 7; ciliary dynein heavy chain 7; dynein heavy chain 7, axonemal; dynein, axonemal, heavy chain 7; dynein, axonemal, heavy polypeptide 7; hDHC2

Molecular Weight

Mass (kDA):
461.159 kDA

Genomic Context


Human

Location:	2q32.3
Sequence:	2; NC_000002.12 (195737604..196068837, complement)

Tissue Specificity

Detected in brain, testis and trachea. Detected in bronchial cells (at protein level).

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium axoneme.

Diseases

Ciliary Motility Disorders
Dyskinetic Syndrome

Pathways

Cell Differentiation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNAH7

References

PMID: 11877439 by Zhang Y.J., et al. Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia.

PMID: 11175280 by Maiti A.K., et al. Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.