DNAH8 Antibodies

AND DNAH8 ELISA kits, DNAH8 Proteins

Many biological assays use antibodies to detect DNAH8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNAH8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNAH8 antibodies...

We validate the specificity of these antibodies to DNAH8 by testing them on tissues known to express DNAH8 positively and negatively. Browse below to find the DNAH8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DNAH8 Overview

Facts about Dynein heavy chain 8, axonemal.

Dynein heavy chain 8, axonemal (DNAH8)

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.

Dynein has ATPase activity; the force-producing power stroke is supposed to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).

Gene Information

Human
Gene Name:	DNAH8
Uniprot:	Q96JB1
Entrez:	1769

Family

Belongs to:

dynein heavy chain family

Alternative Names

ATPase; axonemal; dynein, axonemal, heavy chain 8; dynein, axonemal, heavy polypeptide 8; FLJ25850; FLJ36115; FLJ36334; hdhc9

Molecular Weight

Mass (kDA):
514.664 kDA

Genomic Context


Human

Location:	6p21.2
Sequence:	6; NC_000006.12 (38715311..39030798)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium axoneme.

Diseases

Malignant Neoplasms
Neoplasms
Osteosarcoma
Malignant Bone Neoplasm
Malignant Neoplasm Of Stomach
Primary Neoplasm
Glioma
Malignant Tumor Of Colon

Malignant Paraganglionic Neoplasm
Bone Neoplasms
Sarcoma

Pathways

Cell Cycle

PTMs

Phosphoprotein

Research Areas

Cellular Markers
Growth and Development
Neuronal Cell Markers
Neuroscience
Plasma Membrane Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNAH8

References

PMID: 12297094 by Samant S.A., et al. The T complex distorter 2 candidate gene, Dnahc8, encodes at least two testis-specific axonemal dynein heavy chains that differ extensively at their amino and carboxyl termini.

PMID: 9373155 by Neesen J., et al. Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.