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- Table of Contents
Facts about Dedicator of cytokinesis protein 5.
Together with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (By similarity). .
Mouse | |
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Gene Name: | Dock5 |
Uniprot: | B2RY04 |
Entrez: | 68813 |
Belongs to: |
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DOCK family |
Dedicator of cytokinesis protein 5
Mass (kDA):
214.429 kDA
Mouse | |
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Location: | 14|14 D1 |
Sequence: | 14; |
Highly expressed in lens, where it predominantly localizes to anterior epithelial cells, and is weakly expressed in lens fiber (at protein level). Expressed in brain, eye, lung, spleen and kidney, but not in thymus or peripheral blood leukocytes.
PMID: 9093026 by Iida F., et al. Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
PMID: 9230506 by Song C.-W., et al. A new hereditary cataract mouse with lens rupture.