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- Table of Contents
Facts about Dolichyldiphosphatase 1.
Required for efficient N-glycosylation.
Necessary for maintaining optimal levels of dolichol-linked oligosaccharides.Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate in a significantly lower rate. Doesn't act on phosphatidate.
| Mouse | |
|---|---|
| Gene Name: | Dolpp1 |
| Uniprot: | Q9JMF7 |
| Entrez: | 57170 |

| Belongs to: |
|---|
| dolichyldiphosphatase family |

dolichyl pyrophosphate phosphatase 1LSFR2; dolichyldiphosphatase 1; EC 3.6.1; EC 3.6.1.43; linked to Surfeit genes in Fugu rubripes 2
Mass (kDA):
27.099 kDA

| Mouse | |
|---|---|
| Location: | 2|2 B |
| Sequence: | 2; |
Widely expressed with highest levels in brain, kidney, lung and intestine.


PMID: 10679242 by Inoue S., et al. Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains.
PMID: 12198133 by Rush J.S., et al. Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells.