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DRAM1 Antibodies

AND DRAM1 ELISA kits, DRAM1 Proteins

Many biological assays use antibodies to detect DRAM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DRAM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DRAM1 antibodies...

We validate the specificity of these antibodies to DRAM1 by testing them on tissues known to express DRAM1 positively and negatively. Browse below to find the DRAM1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DRAM1 Infographic by Boster Bio

DRAM1 protein infographic

All DRAM1 Products

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DRAM (DRAM1) (NM_018370) Human Over-expression Lysate

DRAM (DRAM1) Human Over-expression Lysates NM_018370

DRAM (DRAM1) Human Over-expression Lysates NM_018370

Human

$628
Cat # LS055332
20 µg, 100 µg

DRAM1 Overview

Facts about DNA damage-regulated autophagy modulator protein 1.

DRAM1 3D structure

DRAM1 3D structure. Source: alphafold

DNA damage-regulated autophagy modulator protein 1 (DRAM1)

Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not included in p73/TP73- mediated autophagy.

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Gene Information

Human
Gene Name:	DRAM1
Uniprot:	Q8N682
Entrez:	55332

Gene Information

Family

Belongs to:

DRAM/TMEM150 family

Family

Alternative Names

Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; DNA-damage regulated autophagy modulator 1; DRAMFLJ11259

Molecular Weight

Mass (kDA):
26.253 kDA

Molecular Weight

Genomic Context


Human

Location:	12q23.2
Sequence:	12; NC_000012.12 (101877327..101923623)

Subcellular Localizations

Lysosome membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Neoplasms
Innate Immune Response
Communicable Diseases

Disease

Interacting Proteins

C1orf21

Interacting Proteins

Pathways

Autophagy
Transport
Electron Transport
Cell Cycle
Electron Transport Chain
Innate Immune Response
Immune Response

Oxidative Phosphorylation
Glycolysis

Pathways

Research Areas

Cancer

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DRAM1

References

PMID: 16839881 by Crighton D., et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

PMID: 17304243 by Crighton D., et al. p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death.