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Dram2 Antibodies
AND Dram2 ELISA kits, Dram2 Proteins
Many biological assays use antibodies to detect Dram2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dram2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dram2 antibodies...
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Dram2 Overview
Facts about DNA damage-regulated autophagy modulator protein 2.
DNA damage-regulated autophagy modulator protein 2 (Dram2)
Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function.
Induces apoptotic cell death when coexpressed with DRAM1. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dram2 |
| Uniprot: | Q9CR48 |
| Entrez: | 67171 |
Family
| Belongs to: |
|---|
| DRAM/TMEM150 family |
Alternative Names
DNA-damage regulated autophagy modulator 2
Molecular Weight
Mass (kDA):
30.228 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 F2.3 |
| Sequence: | 3; |
Tissue Specificity
Expressed in the retina.
Diseases
- Neoplasms
- Stomach Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Stomach
- Malignant Neoplasms
- Ovarian Neoplasm
Pathways
- Autophagy
- Cell Death
- Secretion
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dram2
bosterbio.com/bosterbio-gene-info-cards/Dram2
References
PMID: 25983245 by El-Asrag M.E., et al. Biallelic mutations in the autophagy regulator DRAM2 cause retinal dystrophy with early macular involvement.