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- Table of Contents
Facts about Down syndrome critical region protein 8.
| Human | |
|---|---|
| Gene Name: | DSCR8 |
| Uniprot: | Q96T75 |
| Entrez: | 84677 |

| Belongs to: |
|---|
| No superfamily |

Down syndrome critical region protein 8
Mass (kDA):
10.969 kDA

| Human | |
|---|---|
| Location: | 21q22.13 |
| Sequence: | 21; NC_000021.9 (38121451..38156511) |
Expressed in numerous tissues; not found in breast, heart, small intestine and liver (PubMed:12036297). Isoform 1: Predominantly expressed in the testis (PubMed:11920614, PubMed:15472897). Isoform 3: Predominantly expressed in the testis, at lower level in the placenta, during malignant progression of melanocytic tumors and in several tumors of varying origins (PubMed:11920614, PubMed:15472897). Isoform 4: Predominantly expressed in the testis, at lower level in the placenta, during malignant progression of melanocytic tumors and in several tumors of varying origins (PubMed:11920614, PubMed:15472897). Isoform 5: Predominantly expressed in the testis (PubMed:11920614, PubMed:15472897). Isoform 6: Predominantly expressed in the testis (PubMed:11920614, PubMed:15472897).

PMID: 11920614 by de Wit N.J., et al. Expression profiling of MMA-1a and splice variant MMA-1b: new cancer/testis antigens identified in human melanoma.
PMID: 12213769 by Toyoda A., et al. Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region.