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- Table of Contents
Desmoglein-3 Antibodies
AND DSG3 ELISA kits, Desmoglein-3 Proteins
Many biological assays use antibodies to detect Desmoglein-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Desmoglein-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Desmoglein-3 antibodies...
Designing a Western blot for Desmoglein-3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DSG3 Western Blot GuideDSG3 Infographic by Boster Bio
All DSG3 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, WB
$370
Cat # A03093
100 μg/vial
Cat # A03093
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03093-2
100 μg
Cat # M03093-2
100 μg
DSG3 Overview
Facts about Desmoglein-3.
Desmoglein-3 (DSG3)
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | DSG3 |
| Uniprot: | P32926 |
| Entrez: | 1830 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Cadherin family member 6; CDHF6; CDHF6130-kD pemphigus vulgaris antigen; desmoglein 3 (pemphigus vulgaris antigen); desmoglein 3; Desmoglein3; Desmoglein-3; DKFZp686P23184,130 kDa pemphigus vulgaris antigen; DSG3; pemphigus vulgaris antigen; PVA
Molecular Weight
Mass (kDA):
107.533 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q12.1 |
| Sequence: | 18; NC_000018.10 (31447741..31478712) |
Tissue Specificity
Epidermis, tongue, tonsil, esophagus and carcinomas.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Diseases
- Autoimmune Reaction
- Bulla
- Tissue Adhesions
- Pemphigus Foliaceus
- Dermatologic Disorders
- Acantholysis
- Autoimmune Diseases
- Mucinous Adenocarcinoma
- Bullous Pemphigoid
- Autoimmunity
- Neoplasms
Pathways
- Cell-cell Adhesion
- Pathogenesis
- Cell Adhesion
- Localization
- Desmosome Assembly
- Secretion
- Cell Proliferation
- Cell Recognition
- Endocytosis
- Telogen
- Keratinocyte Differentiation
- Reverse Transcription
- Rna Interference
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DSG3
bosterbio.com/bosterbio-gene-info-cards/DSG3
References
PMID: 1720352 by Amagai M., et al. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion.