Dystrobrevin alpha Antibodies

AND DTNA ELISA kits, Dystrobrevin alpha Proteins

Many biological assays use antibodies to detect Dystrobrevin alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dystrobrevin alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dystrobrevin alpha antibodies...

We validate the specificity of these antibodies to Dystrobrevin alpha by testing them on tissues known to express DTNA positively and negatively. Browse below to find the DTNA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DTNA Infographic by Boster Bio

All DTNA Products

Product

Figures

Specificity

Applications

Price

Dystrobrevin alpha (DTNA) (NM_032980) Human Recombinant Protein

$1249
Cat # PROTQ9Y4J8
20 µg

Anti-Dystrobrevin alpha (DTNA) Mouse Monoclonal Antibody [Clone ID: OTI1B2]

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M05610
100 µl

Dystrobrevin alpha (DTNA) (NM_032979) Human Over-expression Lysate

Human

$960
Cat # LS001837
100 µg

DTNA Overview

Facts about Dystrobrevin alpha.

DTNA 3D structure. Source: alphafold

Dystrobrevin alpha (DTNA)

May be involved in the formation and stability of synapses in addition to being involved in the clustering of nicotinic acetylcholine receptors. .

Gene Information

Human
Gene Name:	DTNA
Uniprot:	Q9Y4J8
Entrez:	1837

Family

Belongs to:

dystrophin family

Alternative Names

Alpha-dystrobrevin; D18S892EDTN; DRP3FLJ96209; DTN-1; DTN-2; DTN-3; DTN-A; dystrobrevin alpha; dystrobrevin, alpha; Dystrophin-related protein 3; LVNC1

Molecular Weight

Mass (kDA):
83.901 kDA

Genomic Context


Human

Location:	18q12.1
Sequence:	18; NC_000018.10 (34493290..34891844)

Tissue Specificity

Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.

Subcellular Localizations

Cytoplasm. Cell junction, synapse. Cell membrane. In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane.

Diseases

Muscular Dystrophy
Dystrophy
Muscular Dystrophy, Duchenne
Cardiomyopathies
Neuromuscular Diseases
3-methylglutaconic Aciduria Type 2
Left Ventricular Hypertrophy
Hypertrophy
Muscular Dystrophy, Animal
Myopathy
Isolated Noncompaction Of The Ventricular Myocardium
Mycoplasma Infections

Heart Failure
Respiratory Tract Diseases
Cytogenetic Abnormality
Hypertrophic Cardiomyopathy
Idiopathic Cardiomyopathy
Mitochondrial Diseases

Interacting Proteins

CTNNAL1

Pathways

Localization
Mrna Splicing
Pathogenesis
Protein Phosphorylation
Reverse Transcription
Pronephric Duct Development
Receptor Clustering
Cell Differentiation
Muscle Contraction

Lateral Line Development
Metaphase
Oocyte Maturation

PTMs

Phosphorylation
Reduction

Cleavage
Oxidation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DTNA

References

PMID: 8845841 by Sadoulet-Puccio H.M., et al. Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post- synaptic membrane.

PMID: 10735273 by Sadoulet-Puccio H.M., et al. The genomic organization of human dystrobrevin.