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- Table of Contents
Dystrobrevin alpha Antibodies
AND DTNA ELISA kits, Dystrobrevin alpha Proteins
Many biological assays use antibodies to detect Dystrobrevin alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dystrobrevin alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dystrobrevin alpha antibodies...
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DTNA Infographic by Boster Bio
All DTNA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M05610
100 µl
Cat # M05610
100 µl
Human
$960
Cat # LS001837
20 µg, 100 µg
Cat # LS001837
20 µg, 100 µg
DTNA Overview
Facts about Dystrobrevin alpha.
Dystrobrevin alpha (DTNA)
May be involved in the formation and stability of synapses in addition to being involved in the clustering of nicotinic acetylcholine receptors. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DTNA |
| Uniprot: | Q9Y4J8 |
| Entrez: | 1837 |
Family
| Belongs to: |
|---|
| dystrophin family |
Alternative Names
Alpha-dystrobrevin; D18S892EDTN; DRP3FLJ96209; DTN-1; DTN-2; DTN-3; DTN-A; dystrobrevin alpha; dystrobrevin, alpha; Dystrophin-related protein 3; LVNC1
Molecular Weight
Mass (kDA):
83.901 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q12.1 |
| Sequence: | 18; NC_000018.10 (34493290..34891844) |
Tissue Specificity
Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.
Subcellular Localizations
Cytoplasm. Cell junction, synapse. Cell membrane. In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane.
Diseases
- Muscular Dystrophy
- Dystrophy
- Muscular Dystrophy, Duchenne
- Cardiomyopathies
- Neuromuscular Diseases
- 3-methylglutaconic Aciduria Type 2
- Left Ventricular Hypertrophy
- Hypertrophy
- Muscular Dystrophy, Animal
- Myopathy
- Isolated Noncompaction Of The Ventricular Myocardium
- Mycoplasma Infections
Interacting Proteins
- CTNNAL1
Pathways
- Localization
- Mrna Splicing
- Pathogenesis
- Protein Phosphorylation
- Reverse Transcription
- Pronephric Duct Development
- Receptor Clustering
- Cell Differentiation
- Muscle Contraction
PTMs
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DTNA
bosterbio.com/bosterbio-gene-info-cards/DTNA
References
PMID: 8845841 by Sadoulet-Puccio H.M., et al. Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post- synaptic membrane.
PMID: 10735273 by Sadoulet-Puccio H.M., et al. The genomic organization of human dystrobrevin.