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DUS2 Antibodies
AND DUS2 ELISA kits, DUS2 Proteins
Many biological assays use antibodies to detect DUS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUS2 antibodies...
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DUS2 Overview
Facts about tRNA-dihydrouridine(20) synthase [NAD(P)+]-like.
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (DUS2)
Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Negatively regulates the activation of EIF2AK2/PKR. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DUS2 |
| Uniprot: | Q9NX74 |
| Entrez: | 54920 |
Family
| Belongs to: |
|---|
| Dus family |
Alternative Names
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Molecular Weight
Mass (kDA):
55.05 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (68023284..68079320) |
Tissue Specificity
Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level).
Subcellular Localizations
Cytoplasm. Endoplasmic reticulum. Mainly at the endoplasmic reticulum.
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUS2
bosterbio.com/bosterbio-gene-info-cards/DUS2
References
PMID: 15994936 by Kato T., et al. A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
PMID: 18096616 by Mittelstadt M., et al. Interaction of human tRNA-dihydrouridine synthase-2 with interferon- induced protein kinase PKR.