DUSP16 Antibodies

AND DUSP16 ELISA kits, DUSP16 Proteins

Many biological assays use antibodies to detect DUSP16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUSP16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUSP16 antibodies...

We validate the specificity of these antibodies to DUSP16 by testing them on tissues known to express DUSP16 positively and negatively. Browse below to find the DUSP16 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUSP16 Infographic by Boster Bio

All DUSP16 Products

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Applications

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Anti-DUSP16 Antibody

Western blot (WB) analysis of DUSP16 polyclonal antibody at 1:500 dilution
Lane1:The Kidney tissue lysate of Rat(40ug)
Lane2:The Brain tissue lysate of Mouse(40ug)
Lane3:SK-OVCAR3 whole cell lysate(40ug)
Lane4:A549 whole cell lysate(40ug)

Human, Mouse, Rat

$405
Cat # A06264
100ul

Anti-MKP-7 DUSP16 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A06264-1
100ul

DUSP16 (NM_030640) Human Over-expression Lysate

Human

$960
Cat # LS080824
20 µg, 100 µg

Anti-DUSP16 Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # A06264-2
100 μl/vial

DUSP16 Overview

Facts about Dual specificity protein phosphatase 16.

DUSP16 3D structure. Source: alphafold

Dual specificity protein phosphatase 16 (DUSP16)

Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.

Gene Information

Human
Gene Name:	DUSP16
Uniprot:	Q9BY84
Entrez:	80824

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

dual specificity phosphatase 16; EC 3.1.3.16; EC 3.1.3.48; FLJ36298; FLJ40991; KIAA1700MGC129701; MAP kinase phosphatase 7; MAPK phosphatase-7; Mitogen-activated protein kinase phosphatase 7; MKP7dual specificity protein phosphatase 16; MKP-7MGC129702; UBP-M; USP16

Molecular Weight

Mass (kDA):
73.102 kDA

Genomic Context


Human

Location:	12p13.2
Sequence:	12; NC_000012.12 (12473282..12562863, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Inflammation
Acute Lymphocytic Leukemia
Cholangiocarcinoma
Reperfusion Injury
Neoplasm Metastasis
Burkitt Lymphoma
Malignant Neoplasm Of Kidney
Metastatic Malignant Neoplasm To The Lymph Node
Tumor Progression
Malignant Neoplasm Of Breast

Carcinoma
Leukemia, Myelocytic, Acute
Insulin Resistance
Cardiovascular Diseases
Tumor Angiogenesis
Brain Infarction
Myeloid Leukemia

Pathways

Localization
Nuclear Export
Cell Cycle
Methylation
Cell Death
Secretion
Cell Adhesion
Osteoclast Differentiation
Cell Migration
Phagosome Maturation
Cytokine Secretion
Hypersensitivity
Response To Oxidative Stress

Sensitization
Translation
Histone Acetylation
Cell Differentiation
Chromatin Remodeling
Cell Proliferation
Cornification

PTMs

Phosphorylation
Dephosphorylation

Acetylation
Nitrosylation

Methylation

Research Areas

Protein Phosphatase
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUSP16

References

PMID: 11489891 by Masuda K., et al. MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein.

PMID: 14586399 by Hoornaert I., et al. MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation.