DUX4L9 Antibodies

AND DUX4L9 ELISA kits, DUX4L9 Proteins

Many biological assays use antibodies to detect DUX4L9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUX4L9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUX4L9 antibodies...

We validate the specificity of these antibodies to DUX4L9 by testing them on tissues known to express DUX4L9 positively and negatively. Browse below to find the DUX4L9 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUX4L9 Infographic by Boster Bio

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DUX4L9 Overview

Facts about Double homeobox protein 4C.

DUX4L9 3D structure. Source: alphafold

Double homeobox protein 4C (DUX4L9)

May be involved in transcriptional regulation (By similarity). Down-regulates MYOD1 expression and might up-regulate MYF5 expression.

May regulate microRNA (miRNA) transcription, upregulating the expression of some myogenic miRNAs, including MIR1-1, MIR133A2, MIR133B and MIR206. Impairs the differentiation of myoblasts and can be involved in muscle regeneration.

Gene Information

Human
Gene Name:	DUX4L9
Uniprot:	Q6RFH8
Entrez:	100288711

Family

Belongs to:

No superfamily

Alternative Names

Double homeobox protein 4C

Molecular Weight

Mass (kDA):
39.442 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (190021169..190022665, complement)

Tissue Specificity

Expressed in muscles, as well as in primary myoblasts and myotubes (at protein level).

Subcellular Localizations

Nucleus.

Interacting Proteins

DES
IPO13

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUX4L9

References

PMID: 19829708 by Ansseau E., et al. DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.

PMID: 18723017 by Bosnakovski D., et al. DUX4c, an FSHD candidate gene, interferes with myogenic regulators and abolishes myoblast differentiation.