Dual specificity tyrosine-phosphorylation-regulated kinase 1B (DYRK1B)

Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1.

Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.