DAGLA Antibodies

AND DAGLA ELISA kits, DAGLA Proteins

Many biological assays use antibodies to detect DAGLA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DAGLA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DAGLA antibodies...

We validate the specificity of these antibodies to DAGLA by testing them on tissues known to express DAGLA positively and negatively. Browse below to find the DAGLA antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DAGLA Infographic by Boster Bio

All DAGLA Products

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Anti-DGLA DAGLA Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10620
100ul

DAGLA Overview

Facts about Sn1-specific diacylglycerol lipase alpha.

DAGLA 3D structure. Source: alphafold

Sn1-specific diacylglycerol lipase alpha (DAGLA)

Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in cells. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.

Gene Information

Human
Gene Name:	DAGLA
Uniprot:	Q9Y4D2
Entrez:	747

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

C11orf11; DAGL(ALPHA); DAGLALPHA; DGL-alpha; diacylglycerol lipase, alpha; EC 3.1.1.-; KIAA0659; Neural stem cell-derived dendrite regulator; NSDDRchromosome 11 open reading frame 11; sn1-specific diacylglycerol lipase alpha

Molecular Weight

Mass (kDA):
114.952 kDA

Genomic Context


Human

Location:	11q12.2
Sequence:	11; NC_000011.10 (61680184..61747002)

Tissue Specificity

Highly expressed in brain and pancreas.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Spinocerebellar Ataxia 20
Disease Of Adrenal Medulla
Neuralgia
Cell Transformation, Neoplastic
Stenosis
Neoplasms
Pain
Ataxia

Glioma
Ataxia, Spinocerebellar

Interacting Proteins

UPK1B

PTMs

Glycoprotein

Phosphoprotein

Research Areas

Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DAGLA

References

PMID: 14610053 by Bisogno T., et al. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.

PMID: 16051747 by Jung K.-M., et al. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors.