Defal1 Antibodies

AND Defal1 ELISA kits, Defal1 Proteins

Many biological assays use antibodies to detect Defal1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Defal1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Defal1 antibodies...

We validate the specificity of these antibodies to Defal1 by testing them on tissues known to express Defal1 positively and negatively. Browse below to find the Defal1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Defal1 Infographic by Boster Bio

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Defal1 Overview

Facts about Defensin alpha-like protein 1.

Defal1 3D structure. Source: alphafold

Defensin alpha-like protein 1 (Defal1)

Intestinal defense peptide (PubMed:23380721, PubMed:28345637). Has potent antibacterial action against Gram- negative bacteria E.

coli O157:H7, S.typhimurium DT104, and K.

Gene Information

Rat
Gene Name:	Defal1
Uniprot:	Q4JEI2
Entrez:	613220

Family

Belongs to:

alpha-defensin family

Alternative Names

Defensin alpha-like protein 1

Molecular Weight

Mass (kDA):
9.702 kDA

Genomic Context


Rat

Location:	16q12.5
Sequence:	16;

Tissue Specificity

Specifically expressed in small intestine (jejunum and ileum) (PubMed:15494476, PubMed:23380721). Probably expressed by Paneth cells at the base of intestinal crypts (PubMed:23380721). Coexpressed with MMP7 in small intestine (PubMed:23380721).

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Defal1

References

PMID: 15494476 by Patil A., et al. Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

PMID: 23380721 by Patil A.A., et al. Rattusin, an intestinal alpha-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities.