Beta-defensin 4 Antibodies

AND Defb4 ELISA kits, Beta-defensin 4 Proteins

Many biological assays use antibodies to detect Beta-defensin 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Beta-defensin 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Beta-defensin 4 antibodies...

We validate the specificity of these antibodies to Beta-defensin 4 by testing them on tissues known to express Defb4 positively and negatively. Browse below to find the Defb4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Defb4 Infographic by Boster Bio

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Defb4 Overview

Facts about Beta-defensin 4.

Defb4 3D structure. Source: alphafold

Beta-defensin 4 (Defb4)

Exhibits antimicrobial activity against Gram-negative germs and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6.

Can bind to mouse (but not individual ) CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036). .

Gene Information

Mouse
Gene Name:	Defb4
Uniprot:	P82019
Entrez:	56519

Family

Belongs to:

beta-defensin family

Alternative Names

Beta-defensin 4

Molecular Weight

Mass (kDA):
7.129 kDA

Genomic Context


Mouse

Location:	8\|8 A1.3
Sequence:	8;

Tissue Specificity

Tongue, esophagus and trachea.

PTMs

Disulfide bond

Pyrrolidone carboxylic acid

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Defb4

References

PMID: 10922379 by Jia H.P., et al. A novel murine beta-defensin expressed in tongue, esophagus, and trachea.

PMID: 20068036 by Roehrl J., et al. Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells.