Dnmt3c Antibodies

AND Dnmt3c ELISA kits, Dnmt3c Proteins

Many biological assays use antibodies to detect Dnmt3c, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dnmt3c in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dnmt3c antibodies...

We validate the specificity of these antibodies to Dnmt3c by testing them on tissues known to express Dnmt3c positively and negatively. Browse below to find the Dnmt3c antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dnmt3c Infographic by Boster Bio

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Dnmt3c Overview

Facts about DNA (cytosine-5)-methyltransferase 3C.

Dnmt3c 3D structure. Source: alphafold

DNA (cytosine-5)-methyltransferase 3C (Dnmt3c)

DNA methyltransferase that specifically methylates the promoters of evolutionarily young retrotransposons in the male germline (PubMed:27856912). De novo methylation and subsequent repression of transposable elements prevents their mobilization, which is essential for germline integrity (PubMed:27856912).

Gene Information

Mouse
Gene Name:	Dnmt3c
Uniprot:	P0DOY1
Entrez:

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

DNA (cytosine-5)-methyltransferase 3C

Molecular Weight

Mass (kDA):
82.921 kDA

Genomic Context


Mouse

Location:
Sequence:	;

Tissue Specificity

Specifically expressed in testis.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dnmt3c

References

PMID: 27856912 by Barau J., et al. The DNA methyltransferase DNMT3C protects male germ cells from transposon activity.

PMID: 28854222 by Jain D., et al. rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.