DUSP10 Antibodies

AND DUSP10 ELISA kits, DUSP10 Proteins

Many biological assays use antibodies to detect DUSP10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUSP10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUSP10 antibodies...

We validate the specificity of these antibodies to DUSP10 by testing them on tissues known to express DUSP10 positively and negatively. Browse below to find the DUSP10 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for DUSP10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the DUSP10 Western Blot Guide

Designing an IHC experiment for DUSP10? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the DUSP10 IHC Guide

DUSP10 Infographic by Boster Bio

All DUSP10 Products

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Product

Figures

Specificity

Applications

Price

DUSP10 (NM_007207) Human Over-expression Lysate

DUSP10 Human Over-expression Lysates NM_007207

Human

$628
Cat # LS011221
20 µg, 100 µg

Anti-MKP-5 DUSP10 Antibody

Western Blot analysis of 3T3 cells using MKP-5 Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded human meningioma

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A05412
100ul

Human DUSP10 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Enzyme Activity, SDS-PAGE

$235
Cat # PROTQ9Y6W6
Starting from 10ug

DUSP10 Overview

Facts about Dual specificity protein phosphatase 10.

DUSP10 3D structure. Source: alphafold

Dual specificity protein phosphatase 10 (DUSP10)

Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.

It rather dephosphorylates p38. .

Gene Information

Human
Gene Name:	DUSP10
Uniprot:	Q9Y6W6
Entrez:	11221

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

dual specificity phosphatase 10; dual specificity phosphatase MKP-5; EC 3.1.3.16; EC 3.1.3.48; MAP kinase phosphatase 5; Mitogen-activated protein kinase phosphatase 5; MKP-5dual specificity protein phosphatase 10; MKP5serine/threonine specific protein phosphatase

Molecular Weight

Mass (kDA):
52.642 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (221701420..221742176, complement)

Tissue Specificity

Detected in brain.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Inflammation
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Malignant Paraganglionic Neoplasm
Cell Invasion
Adenocarcinoma
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Tumor Angiogenesis

Posttransfusion Purpura
Physiological Stress
Inflammatory Response
Autoimmunity
Diabetic Nephropathy
Malignant Tumor Of Colon
Glioma

Interacting Proteins

MAPK9

Pathways

Cell Proliferation
Cell Cycle Arrest
Inflammatory Response
Cell Cycle
Localization
Angiogenesis
Rna Interference
Transport
Aging
Immune Response
Response To Oxidative Stress
Interleukin-6 Production
Translation

Response To Uv
Mrna Stabilization
Cell Communication
Liver Regeneration
Oligodendrocyte Differentiation
Response To Stress
Induction Of Apoptosis

PTMs

Phosphorylation

Dephosphorylation

Cleavage

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUSP10

References

PMID: 10391943 by Tanoue T., et al. Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5.

PMID: 10597297 by Theodosiou A., et al. MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases.