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- Table of Contents
Facts about ELL-associated factor 2.
Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.
| Human | |
|---|---|
| Gene Name: | EAF2 |
| Uniprot: | Q96CJ1 |
| Entrez: | 55840 |

| Belongs to: |
|---|
| EAF family |

BM040; ELL associated factor 2; testosterone regulated apoptosis inducer and tumor suppressor; Testosterone-regulated apoptosis inducer and tumor suppressor protein; TRAITSELL-associated factor 2; U19
Mass (kDA):
28.792 kDA

| Human | |
|---|---|
| Location: | 3q13.33 |
| Sequence: | 3; NC_000003.12 (121835180..121886526) |
Expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes.
Nucleus speckle.





PMID: 12446457 by Simone F., et al. ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
PMID: 12907652 by Xiao W., et al. Suppression of prostate tumor growth by U19, a novel testosterone- regulated apoptosis inducer.