ECEL1 Antibodies

AND ECEL1 ELISA kits, ECEL1 Proteins

Many biological assays use antibodies to detect ECEL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ECEL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ECEL1 antibodies...

We validate the specificity of these antibodies to ECEL1 by testing them on tissues known to express ECEL1 positively and negatively. Browse below to find the ECEL1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ECEL1 Infographic by Boster Bio

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ECEL1 (NM_004826) Human Over-expression Lysate

Human

$628
Cat # LS009427
100 µg

ECEL1 Overview

Facts about Endothelin-converting enzyme-like 1.

ECEL1 3D structure. Source: alphafold

Endothelin-converting enzyme-like 1 (ECEL1)

May contribute to the degradation of peptide hormones and participate in the inactivation of neuronal peptides. .

Gene Information

Human
Gene Name:	ECEL1
Uniprot:	O95672
Entrez:	9427

Family

Belongs to:

peptidase M13 family

Alternative Names

damage induced neuronal endopeptidase; DINE; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.11; ECEX; endothelin converting enzyme-like 1; endothelin-converting enzyme-like 1; Xce protein; XCEX converting enzyme

Molecular Weight

Mass (kDA):
87.791 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (232479827..232487834, complement)

Tissue Specificity

Highly expressed in the CNS, in particular in putamen, spinal cord, medulla and subthalamic nucleus. A strong signal was also detected in uterine subepithelial cells and around renal blood vessels. Detected at lower levels in amygdala, caudate, thalamus, pancreas and skeletal muscle. Detected at very low levels in substantia nigra, cerebellum, cortex, corpus callosum and hippocampus.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Nervousness
Neoplasms
Pituitary Diseases
Malignant Neoplasms
Neuroblastoma
Crest Syndrome
Keratosis
Neoplasm Metastasis
Disease Of Adrenal Medulla
Hyperpigmentation
Craniocerebral Trauma
Peripheral Nerve Injuries

Tumor Progression
Hypoxia
Bone Neoplasms
Renal Vascular Disorder
Hypophosphatemia
Sleep Disorders
Malignant Neoplasm Of Urinary Bladder

Pathways

Localization
Secretion
Methylation
Transport
Regeneration
Cell Proliferation
Programmed Cell Death
Cell Death

Response To Hypoxia
Dna Methylation
Pigmentation

PTMs

Biotinylation

Cleavage

Methylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ECEL1

References

PMID: 9931490 by Valdenaire O., et al. XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS.

PMID: 10698686 by Valdenaire O., et al. Organization and chromosomal localization of the human ECEL1 (XCE) gene encoding a zinc metallopeptidase involved in the nervous control of respiration.