Edem3 Antibodies

AND Edem3 ELISA kits, Edem3 Proteins

Many biological assays use antibodies to detect Edem3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Edem3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Edem3 antibodies...

We validate the specificity of these antibodies to Edem3 by testing them on tissues known to express Edem3 positively and negatively. Browse below to find the Edem3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Edem3 Infographic by Boster Bio

All Edem3 Products

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Product

Figures

Specificity

Applications

Price

Anti-EDEM3 Antibody

Western Blot analysis of Hela lysis, using primary antibody at 1:1000 dilution

Human, Mouse

ELISA, WB

$380
Cat # A10297
100ul

Anti-EDEM3 Antibody Picoband®

Western blot analysis of EDEM3 using anti-EDEM3 antibody (A10297-2)

IHC analysis of EDEM3 using anti-EDEM3 antibody (A10297-2)

Human

ELISA, IHC, WB

$370
Cat # A10297-2
100 μg/vial

EDEM3 (NM_025191) Human Over-expression Lysate

Human

$960
Cat # LS080267
20 µg, 100 µg

Edem3 Overview

Facts about ER degradation-enhancing alpha-mannosidase-like protein 3.

ER degradation-enhancing alpha-mannosidase-like protein 3 (Edem3)

Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 from the N-glycans.

Seems to have alpha 1,2-mannosidase activity. .

Gene Information

Mouse
Gene Name:	Edem3
Uniprot:	Q2HXL6
Entrez:	66967

Family

Belongs to:

glycosyl hydrolase 47 family

Alternative Names

C1orf22; chromosome 1 open reading frame 22; ER degradation enhancer, mannosidase alpha-like 3; ER degradation-enhancing alpha-mannosidase-like 3; ER degradation-enhancing -mannosidase-like protein 3

Molecular Weight

Mass (kDA):
104.2 kDA

Genomic Context


Mouse

Location:	1\|1 G1-G2
Sequence:	1;

Tissue Specificity

Widely expressed. Expressed at higher level in liver, heart and kidney.

Diseases

Infective Disorder
Hepatitis
Japanese Encephalitis
Amyloidosis, Familial
Amyloidosis
Hepatitis B
Hepatitis C
Virus Diseases
Mucopolysaccharidoses
Lysosomal Storage Diseases

Mucopolysaccharidosis I
Encephalitis
Mucopolysaccharidosis Type Iiib
Inflammation

Pathways

Cell Proliferation
Protein Folding
Pathogenesis
Secretion

PTMs

Glycosylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Edem3

References

PMID: 16431915 by Hirao K., et al. EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.

PMID: 17499246 by Olivari S., et al. Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins.