EP300-interacting inhibitor of differentiation 2 (EID2)

Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity.

Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by blocking formation of TGFB-induced SMAD3-SMAD4 complex.