EIF2S3B Antibodies

AND EIF2S3B ELISA kits, EIF2S3B Proteins

Many biological assays use antibodies to detect EIF2S3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2S3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2S3B antibodies...

We validate the specificity of these antibodies to EIF2S3B by testing them on tissues known to express EIF2S3B positively and negatively. Browse below to find the EIF2S3B antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2S3B Infographic by Boster Bio

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EIF2S3B Overview

Facts about Eukaryotic translation initiation factor 2 subunit 3B.

EIF2S3B 3D structure. Source: alphafold

Eukaryotic translation initiation factor 2 subunit 3B (EIF2S3B)

As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation.

This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex.

Gene Information

Human
Gene Name:	EIF2S3B
Uniprot:	Q2VIR3
Entrez:	255308

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

Eukaryotic translation initiation factor 2 subunit 3B

Molecular Weight

Mass (kDA):
51.229 kDA

Genomic Context


Human

Location:	12p13.2
Sequence:	12; NC_000012.12 (10505893..10523135)

Tissue Specificity

Specifically expressed in testis at the mRNA level.

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2S3B

References

PMID: 16201836 by Marques A.C., et al. Emergence of young human genes after a burst of retroposition in primates.

PMID: 9736774 by Ehrmann I.E., et al. Characterization of genes encoding translation initiation factor eIF- 2gamma in mouse and human: sex chromosome localization, escape from X- inactivation and evolution.