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The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and then prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632).
|eIF-3 subunit G family|
|Sequence:||19; NC_000019.10 (10115014..10119899, complement)|
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Colocalizes with AIFM1 in the nucleus and perinuclear region.