Elongation of very long chain fatty acids protein 4 (ELOVL4)

Catalyzes the first and rate-limiting reaction of the four which constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic procedure, allows the addition of two carbons into the string of long- and very long-chain fatty acids/VLCFAs each cycle.

Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate in the production of polyunsaturated and saturated VLCFAs of different chain lengths which are involved in several biological processes as precursors of membrane lipids and lipid mediators.