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Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate in the production of polyunsaturated and saturated VLCFAs of different chain lengths which are involved in several biological processes as precursors of membrane lipids and lipid mediators.
|Sequence:||6; NC_000006.12 (79914814..79947553, complement)|
Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates.
Endoplasmic reticulum membrane; Multi-pass membrane protein.