EMSY Antibodies

AND EMSY ELISA kits, EMSY Proteins

Many biological assays use antibodies to detect EMSY, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EMSY in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EMSY antibodies...

We validate the specificity of these antibodies to EMSY by testing them on tissues known to express EMSY positively and negatively. Browse below to find the EMSY antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EMSY Infographic by Boster Bio

All EMSY Products

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Anti-C11orf30/EMSY Antibody Picoband®

Western blot analysis of C11orf30/EMSY using anti-C11orf30/EMSY antibody (A04477-1)

IHC analysis of C11orf30/EMSY using anti-C11orf30/EMSY antibody (A04477-1)

IF analysis of C11orf30/EMSY using anti-C11orf30/EMSY antibody (A04477-1) and anti-Alpha Tubulin antibody (M03989-3)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04477-1
100 μg/vial

EMSY Overview

Facts about BRCA2-interacting transcriptional repressor EMSY.

EMSY 3D structure. Source: alphafold

BRCA2-interacting transcriptional repressor EMSY (EMSY)

Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.

As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. .

Gene Information

Human
Gene Name:	EMSY
Uniprot:	Q7Z589
Entrez:	56946

Family

Belongs to:

No superfamily

Alternative Names

BRCA2-interacting transcriptional repressor EMSY

Molecular Weight

Mass (kDA):
141.468 kDA

Genomic Context


Human

Location:	11q13.5
Sequence:	11; NC_000011.10 (76444928..76553031)

Subcellular Localizations

Nucleus. Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.

Interacting Proteins

CBX1
ZNF646

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EMSY

References

PMID: 14651845 by Hughes-Davies L., et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.

PMID: 19131338 by Garapaty S., et al. Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.