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- Table of Contents
Facts about Ectonucleoside triphosphate diphosphohydrolase 3.
Has a threefold preference for the hydrolysis of ATP over ADP.
.Human | |
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Gene Name: | ENTPD3 |
Uniprot: | O75355 |
Entrez: | 956 |
Belongs to: |
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GDA1/CD39 NTPase family |
ATPDase; CD39 antigen-like 3; CD39L3; CD39L3EC 3.6.1.5; CD39-like 3; EC 3.6.1; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; ectonucleoside triphosphate diphosphohydrolase 3; ENTPD3; FLJ93839; HB6; HB6NTPDase 3; NTPDase-3
Mass (kDA):
59.105 kDA
Human | |
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Location: | 3p22.1 |
Sequence: | 3; NC_000003.12 (40387182..40428744) |
Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
Membrane; Multi-pass membrane protein.
PMID: 9676430 by Chadwick B.P., et al. The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.
PMID: 9675246 by Smith T.M., et al. Cloning, sequencing, and expression of a human brain ecto-apyrase related to both the ecto-ATPases and CD39 ecto-apyrases.