Ectonucleoside triphosphate diphosphohydrolase 8 (Entpd8)

Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides.

Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. .