ENY2 Antibodies

AND ENY2 ELISA kits, ENY2 Proteins

Many biological assays use antibodies to detect ENY2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ENY2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ENY2 antibodies...

We validate the specificity of these antibodies to ENY2 by testing them on tissues known to express ENY2 positively and negatively. Browse below to find the ENY2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENY2 Infographic by Boster Bio

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ENY2 (NM_020189) Human Over-expression Lysate

Human

$628
Cat # LS056943
20 µg, 100 µg

ENY2 Overview

Facts about Transcription and mRNA export factor ENY2.

ENY2 3D structure. Source: alphafold

Transcription and mRNA export factor ENY2 (ENY2)

Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.

Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators like MYC, where it is required for transcription.

Gene Information

Human
Gene Name:	ENY2
Uniprot:	Q9NPA8
Entrez:	56943

Family

Belongs to:

ENY2 family

Alternative Names

DC6; enhancer of yellow 2 homolog (Drosophila)

Molecular Weight

Mass (kDA):
11.529 kDA

Genomic Context


Human

Location:	8q23.1
Sequence:	8; NC_000008.11 (109334347..109345954)

Subcellular Localizations

Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Localization at the nuclear pore complex requires NUP153 and TPR.

Diseases

Malignant Neoplasms
Neoplasms
Insulinoma
Malignant Neoplasm Of Breast
Second Primary Malignancy
Diabetes Mellitus

Pathways

Translation
Nuclear Export
Insulin Secretion
Histone Acetylation
Mrna Processing
Cell Growth

Secretion

PTMs

Acetylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENY2

References

PMID: 11438676 by Georgieva S., et al. The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.

PMID: 18206972 by Zhao Y., et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.